Ceftriaxone has a powerful effect on Escherichia coli, Pneumoniae, Indole-positive Proteus, Influenzae, Serratia, Meningococcus, and Neisseria gonorrhoeae; Pneumococcus, Streptococcus and Staphylococcus aureus are moderately sensitive to this product; It has a certain effect on Pseudomonas aeruginosa. Enterococcus, methicillin-resistant Staphylococcus and most Bacteroides fragilis are resistant to this product.